THE FREQUENCY OF X-RAY INDUCED DOMINANT MUTATIONS AFFECTING THE SKELETON OF MICE
نویسندگان
چکیده
منابع مشابه
The Frequency of X-ray Induced Dominant Mutations Affecting the Skeleton of Mice.
ADIATION induced dominant effects on viability in mammals are statistically demonstrable (HERTWIG 1938; RUSSELL 1957; RUSSELL and RUSSELL 1958; Cox and WILLHAM 1962). RUSSELL and RUSSELL 1959) emphasized that these effects may well prove to add up to a greater damage in the population than the lethal effects of mutations in homozygous condition. However, very little is known about the rate at w...
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D O M I N A N T radiation-induced genetic damage can be measured by comparing first-generation descendants from irradiated and unirradiated populations, but, for many characters, it is difficult to distinguish between the effects of newly occurring genetic changes and the within-strain variation. This problem has been solved for a large group of skeletal abnormalities by a method described earl...
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P A R T of the genetic damage induced by X rays may be due to mutations which have harmful effects on viability. Such mutations may vary in the seventy of their effects from lethal to mildly detrimental, and in degree of dominance from completely dominant or overdominant to completely recessive. The difficulties of obtaining precise mutation rate estimates for viability mutations in mammals are...
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ژورنال
عنوان ژورنال: Genetics
سال: 1965
ISSN: 1943-2631
DOI: 10.1093/genetics/51.5.723